Free radicals

February 3, 2025
Published
Last updated
February 3, 2025
Immanuels' Key takeaways
  1. Free Radicals are unstable molecules that can cause oxidative damage to cells, proteins, and DNA, contributing to ageing and the development of chronic diseases like cancer and heart disease.
  2. Antioxidants neutralise free radicals, helping to protect the body from oxidative stress and reducing the risk of long-term health issues.

Free radicals are highly reactive molecules with unpaired electrons, created during normal metabolic processes and through environmental factors like pollution, smoking, and UV radiation. These molecules can cause damage to cells and DNA, leading to a condition called oxidative stress, which is linked to ageing and chronic diseases like cancer and heart disease.

What Are Free Radicals?

Free radicals are unstable molecules that seek to stabilise by “stealing” electrons from other molecules, resulting in cellular damage. This damage can affect DNA, proteins, and lipids, contributing to various health conditions.

How Do Free Radicals Cause Damage?

When free radicals attack cells, they can:

  1. Damage DNA, potentially leading to mutations and cancer.
  2. Disrupt proteins, contributing to diseases like Alzheimer's.
  3. Attack lipids, increasing the risk of conditions like atherosclerosis.

The Role of Antioxidants

Antioxidants are compounds which neutralise free radicals by donating electrons, preventing cellular damage. Key antioxidants include Vitamin C, Vitamin E, beta-carotene, and flavonoids, found in fruits, vegetables, and whole grains.

Free radicals play a significant role in cellular damage and disease development. However, antioxidants help protect the body by neutralising these harmful molecules. By consuming antioxidant-rich foods and maintaining a healthy lifestyle, we can reduce the effects of oxidative stress and support long-term health.

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Sources of Free Radicals

Free radicals are produced during normal metabolism but are also generated by:

  1. Pollution and chemicals.
  2. UV radiation from the sun.
  3. Smoking and alcohol consumption.
Health Implications

Excessive free radicals can lead to:

  1. Cancer from DNA damage.
  2. Heart disease due to arterial damage.
  3. Neurodegenerative disorders like Alzheimer's.
  4. Premature ageing.

Related terms

  1. Oxidative Stress: The imbalance between free radicals and antioxidants, leading to cellular damage.
  2. Antioxidants: Compounds that neutralise free radicals and protect the body from oxidative damage.